There are few better ways to experience autumn in Italy than with a trip to its wine regions, visiting vineyards and cantinas, sampling artisanal cheeses and breads, and dining in rustic trattorias  overlooking poster-worthy landscapes.

But Italy has some 140 wine roads (called strade dei vini) to sate most every oenophile’s taste, so how to choose one that’s best for you? Here are five of these amazing routes, ranging from the Veneto and Piedmont in the north to Sicily in the south for you to consider for your next fall getaway.