The team behind San Diego's Ambrogio15 restaurants has opened Ambrogio15 Enoteca, a wine room and grocery now open in the former Ciao Ciao Piadina space in La Jolla. Milan-turned-San Diego residents Giacomo Pizzigoni, Andrea Burrone and Luca Salvi opened the flagship Ambrogio15 on Turquoise Street in San Diego's North Pacific Beach community in August 2016.

The team expanded in 2018 with a stall within the Little Italy Food Hall and also opened a micro-version of Ambrogio15 within Del Mar Highlands Town Center's 20,000 square-foot, multi-restaurant food hall The Sky Deck. The Ambrogio boys launched new concept Semola Artisan Express Pasta in the Little Italy Food Hall in 2019 but last year relocated the concept to the indoor/outdoor La Jolla space left dormant by the sudden and inexplicable closure of PrepKitchen.